The purpose of pull up/down is to insure that a circuit has a default value (high, or low), given no other input:
a pull up resistor (connect to a power supply) pulls the line high;
a pull down resistor(connect to ground) pulls the line down.
Pull-up resistor pull-down
MON_INT_N is connected to OM5_GPIO8_233. INT2 pad can be configured as active high; GPIO is configured as input (internal pull up/pull down disabled; high level detection).
When MON drives 3.3V (high), the downside of R14130, closer to MON, is 2.5V due to 1.8V (R13993) pull-up.
Note: INT2 pad can be configured to open-drain, too. I assume that the “NB” resisters are there, in case the pad is configured as open drain?